ABSTRACT
Neuromyelitis optica spectrum disorders (NMOSD) is a demyelinating syndrome of the central nervous system. This case report describes a 31-year-old woman whose electromyography revealed radiculopathy in the left L5-S1 spinal segment without anatomical abnormalities on lumbosacral magnetic resonance imaging (MRI). She was diagnosed with NMOSD based on gadolinium contrast whole spine and brain MRI and anti-aquaporin-4 antibody findings. Her peripheral nervous system might have been damaged during the early course of NMOSD. Therefore, it is necessary to consider NMOSD for patients who have radiculopathy in electromyography if lumbosacral MRI shows no abnormalities.
Subject(s)
Adult , Female , Humans , Brain , Central Nervous System , Electromyography , Gadolinium , Magnetic Resonance Imaging , Neuromyelitis Optica , Peripheral Nervous System , Peripheral Nervous System Diseases , Radiculopathy , SpineABSTRACT
PURPOSE: This study was done to evaluate the validity of Korean Denver II developmental screening test in screening children with developmental risk. METHOD: The participants in the study were 113 children referred for developmental assessment in the department of rehabilitation of D University hospital. They were examined with the BSID (Bayley Scales of Infant Development) II and Korean Denver II by one occupational therapist. The data was analyzed by Chi square test and discriminant analysis. RESULTS: There was a significant relationship between the Mental Developmental Index (MDI) of the BSID II and the result of the Korean Denver II. The sensitivity and specificity of Korean Denver II were 0.87 and 0.62 when abnormal MDI was defined as lower than 85 was used as a diagnosis of developmental delay. There was a significant relationship between the Psychomotor Developmental Index (PDI) of the BSID II and the result of Korean Denver II. The sensitivity and specificity of Korean Denver II were 0.83 and 0.51. The over-all hit ratio was 79.6%. CONCLUSION: The result showed that the Korean Denver II was valid and has good sensitivity and moderate specificity in screening developmental delay.